Research and innovation play a pivotal role in achieving the overarching objectives of the EU and are essential for addressing urgent societal, global and economic challenges such as climate crisis, health, and the digital transformation. The Belgian Presidency will therefore prioritise the contribution of research and innovation as our foremost catalyst for achieving greater open strategic autonomy for Europe, while focusing on better valorisation of research results and reinforcing the role of research and innovation in society to overcome key industrial and societal challenges. The Belgian Presidency acknowledges the importance of space activities as a strategic asset, particularly in domains such as security, defense, climate change mitigation, and the empowerment of New Space actors. It will aim to advance cybersecurity and secure connectivity and to promote the safe, sustainable, and secure use of space. In dealing with these challenges, including also responsible international cooperation, the commitment to nurturing the EU’s open strategic autonomy will run as a common thread.