| Source DB | nl |
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| Institution | KU Leuven |
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| Code | 9b079f1d-ac46-4355-a3d0-765d65876388 |
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| Unit | f2bf5275-c166-4fa0-9046-65ef450faacb
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| Begin | 1/1/2018 |
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| End | 12/31/2021 |
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| title fr |
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| title nl | Opvolging van Stralingsdosis en Radiobiologische Effecten van Tandheelkundige Bestralingen
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| title en | Tracking of Radiation Dose and Radiobiological Effects of Dental Exposures
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| Description fr |
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| Description nl | Om de kennis over de effecten van blootstelling aan straling in de tandheelkunde te vergroten, wil dit project een radiobiologische studie uitvoeren met speciale aandacht voor subtiele veranderingen in componenten van de orofaciale regio (cellen en speeksel) van patiënten na blootstelling aan lage doses röntgenstraling .
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| Description en | There is a lot of controversy and uncertainty regarding the potential harmful effects of radiation at low doses. A particular field in which the characterization of these effects is of great importance is dentistry, due to the high frequency of radiographic exposures. Recently, the introduction of conebeam computed tomography (CBCT) has exacerbated the situation; as its use has increased exponentially in the last decade, including for children. To increase the knowledge on the effects of radiation exposures in dentistry, this project aims to conduct a radiobiology study with a special focus on subtle changes in components of the orofacial region (cells and saliva) of patients after exposure to low doses of X-rays. The first work package (WP), targets to deliver predictive models of the behavior of the complex systems, represented by the tooth and its surrounding cellular components, to low radiation doses. These models allow a better biological understanding of the risks from low doses and low dose rates exposure. In a second work package, a tool will be developed which allows for patient-specific radiation dose estimations for any radiographic technique used in dentistry. This tool will not only be used to characterize the doses used in WP1, but has several longterm applications, including dose tracking/monitoring, optimization and epidemiological research. The two WPs will be combined into a "radiation passport" which tracks individual dose and potential risk.
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| Qualifiers | - Dental exposures - Radiation - Radiobiological effects - X-rays - |
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| Personal | Jacobs Reinhilde |
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